Musculoskeletal diseasesVersatile use of our therapies – based on scientific studies

targeted and autologousFrequent Musculoskeletal Conditions

Molecular orthopedics has long shown that many orthopedic diseases are conditions not merely generated by mechanical wear and tear but result from a complex interplay of mechanical, molecular and biochemical signals.

Most orthopedic diseases are impacted by inflammation, other biomolecular changes and often regenerative deficiency in the short- or long-term. These factors are ascribed to diseases of any tissue type including joints, nerves, muscles, tendons.

To give an example: Osteoarthritis is a highly prevalent chronic disease with rising incidence, that could potentially affect anyone throughout lifetime. Osteoarthritis is commonly perceived as a widespread incurable but harmless condition. However, the disease actually constitutes an undervalued international health crisis. Osteoarthritis is associated with severe individual suffering, serious comorbidities, premature mortality and a large financial socioeconomic burden (OARSI White Paper, 2016).

Currently approved treatment options are largely palliative (suppressing symptoms) without a regenerative effect. By scientific consensus, the spectrum of currently available treatments is limited and lacks appropriate efficacy as well as safety. Many are associated with severe risks including cardiovascular diseases, gastric bleeding, persistent disability and premature death. Analgesics overuse cannot merely lead to severe consequences individually but also socioeconomically, as the opioid crisis has demonstrated.

Generally speaking, the critical unmet medical need in orthopedic diseases –with osteoarthritis as an exemplar disease– needs to be addressed efficiently, at the core of the problem and not only by suppressing symptoms until surgery is said to be unavoidable.

We intend to address these issues with our methods in a scientific, robust manner.